High Security Animal Disease Laboratory

Indian Veterinary Research Institute, Indian Council of Agricultural Research

         Institute Funded Research Projects

 INSTITUTE FUNDED RESEARCH PROJECTS

Current Projects

1. Surveillance of exotic and emerging animal diseases in Indian and imported livestock & poultry and their products.

With sub-projects on

• Avian Influenza epidemiology.

• Performance optimization of SPF facility for Influenza research

• Swine Influenza

• BVD/ BD

• Other exotic diseases of livestock and Poultry

2. Development and evaluation of referral group specific and subtype specific diagnostic reagent of Avian Influenza.

3. Molecular characterization of Avian Influenza viruses isolated in India.

4. Evaluation of H9N2 virus induced alteration in the progression of H5N1 virus infection in chickens.

5. Identification of transcriptomics variations of duck and crow in response to evolving Avian influenza virus.

6. Quest for a Universal Diagnostic PCR Array for multiple exotic and emerging viral diseases.

7. Identification of Neuraminidase inhibitor drug resistance in H5N1 viruses isolated from India.

8. Cross-sectional surveillance of Malignant Catarrhal Fever infection in domestic and wild ruminants in Southern India.

    

Completed Projects

1. MicroRNA profiling of lung tissue of chicken infected with avian influenza virus.

2. Development of Real-Time PCR for diagnosis of Crimean Congo Hemorrhagic fever.

3. Screening and evaluation of various herbal extracts against highly pathogenic avian influenza virus.

4. Study of inhibitory potential of small interfering RNAs as directed against various gene segments of avian influenza  H5N1 virus.

5. Pathogenic characterization of Indian AI virus.

6. Development of yeast-expressed recombinant antigens for diagnosis and immunoprophylaxis of AI virus.

7. Environmental Persistence of Avian Influenza virus.

8. Development of one step TaqMan Real Time RT-PCR for detection and genetic typing of ruminant pestivirus.

9. Development of monoclonal antibodies and recombinant antibodies against bovine immunodeficiency virus.

10. Pathobiology of acute and persistent infection of bovine viral diarrhea in small ruminants.

11. Molecular diagnosis and pathobiology of porcine circovirus and parvovirus infections in correlation to viral wasting syndrome of swine.

12. Development of monoclonal antibody based immunoassay for diagnosis of avian influenza.

13. Survivability of H5N1 avian influenza virus under different physical conditions.

14. Sero-epidemiology and molecular diagnosis of type A influenza virus in poultry.

15. Development of molecular diagnostics and enzyme immunoassay for caprine arthritis and encephalitis infection in goats.

16. Development of diagnostic technique for the detection of Rabbit Hemorrhagic Disease (RHD) in India.

17. Development of enzyme immunoassay and nucleic acid based diagnostic tests for the detection of porcine reproductive and respiratory syndrome in pigs.

18. Development of diagnostic technique for the detection transmissible gastro-enteritis (TGE) virus infection in pigs in India.

19. Impact of biotic and abiotic stress on the pathogenicity of H9N2 influenza A virus in chicken.

20. Evaluation of killed H5N1 vaccine and studies on its production aspects.